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About Thalassemia
Signs & Symptoms of Beta Thalassemia Intermedia or Major
Children with beta thalassemia intermedia or major may not show any symptoms at birth, but usually develop anaemia in the first 2 years of life. Signs of anaemia in beta thalassemia intermedia or major may include:
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Extreme tiredness
![](https://samraksha.rashtrotthana.org/wp-content/uploads/2024/03/moisturizing.png)
Pale skin
![](https://samraksha.rashtrotthana.org/wp-content/uploads/2024/03/breath.png)
Shortness of breath
![](https://samraksha.rashtrotthana.org/wp-content/uploads/2024/03/heartbeat.png)
Fast heartbeat
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Irritability
![](https://samraksha.rashtrotthana.org/wp-content/uploads/2024/03/slow-growth.png)
Slow or delayed growth
![](https://samraksha.rashtrotthana.org/wp-content/uploads/2024/03/irritation.png)
Change in the shape of bones in the face and head
People with beta thalassemia intermedia or major also build-up extra iron in the body, either from the disease itself or from frequent blood transfusions. Extra iron can get deposited and damage the heart, liver, and endocrine system. To prevent that they need to take Regularly a special Medication called Iron Chelator.
![](https://samraksha.rashtrotthana.org/wp-content/uploads/2024/02/vector.png)
People with beta thalassemia major may have other serious complications if not managed properly including:
Bone deformities from changes in the bone marrow (where RBCs are made)
An enlarged spleen and Liver. Doctors might need to remove the spleen if it gets too big or causes pain
Gallstones. Doctors might need to remove the gallbladder if the stones cause pain or infection
Infections, especially if doctors removed the spleen (the spleen helps fight some infections)
Diabetes from damage to the pancreas and endocrine system